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Updated: Feb 6, 2026

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis
Joseph Tadros1, Stacey Goodman2,3, Eric R Tkaczyk2,3,4
1University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Abstract:
We present a case of subcutaneous nodular amyloidosis mimicking a pilar cyst. Further evaluation led to the diagnosis of malignant systemic light-chain amyloidosis. The epidemiology and histopathological features of light-chain amyloidosis with cutaneous involvement are reviewed, as well as current recommendations for initial evaluation.
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