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Updated: Feb 6, 2026

Collection and Identification of Pollen from Honey Bee Colonies
Published on: January 19, 2021
Polyamine derivatives from the bee pollen of Quercus mongolica with tyrosinase inhibitory activity
Seon Beom Kim1, Qing Liu1, Jong Hoon Ahn1
1College of Pharmacy, Chungbuk National University, Cheongju 28160, Republic of Korea.
Abstract:
Eighteen constituents, including nine new compounds, were isolated from the bee pollen of Quercus mongolica. The structures of the new compounds were established on the basis of combined spectroscopic analysis. Structurally, the nine new compounds are polyamine derivatives with phenolic moieties which were assigned as one putrescine derivative, mogolicine A (2), seven spermidine derivatives, mongolidines A-G (3-5, 8, 12, 14, 17) and one spermine derivative, mogoline A (18). Evaluation of the biological activity of isolated compounds revealed that the polyamine derivatives with coumaroyl and caffeoyl moieties showed tyrosinase inhibition with IC50 values of 19.5-85.8 μM; however, the addition of a methoxy group to phenolic derivatives reduced the inhibitory activity.
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