Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Oscillations In An LC Circuit

Oscillations In An LC Circuit

An idealized LC circuit of zero resistance can oscillate without any source of emf by shifting the energy stored in the circuit between the electric and magnetic fields. In such an LC circuit, if the capacitor contains a charge q before the switch is closed, then all the energy of the circuit is initially stored in the electric field of the capacitor. This energy is given by

Forced Oscillations

Forced Oscillations

When an oscillator is forced with a periodic driving force, the motion may seem chaotic. The motions of such oscillators are known as transients. After the transients die out, the oscillator reaches a steady state, where the motion is periodic, and the displacement is determined.

Damped Oscillations

Damped Oscillations

In the real world, oscillations seldom follow true simple harmonic motion. A system that continues its motion indefinitely without losing its amplitude is termed undamped. However, friction of some sort usually dampens the motion, so it fades away or needs more force to continue. For example, a guitar string stops oscillating a few seconds after being plucked. Similarly, one must continually push a swing to keep a child swinging on a playground.
Although friction and other non-conservative...

Outcomes of Glycolysis

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...

Predicting Reaction Outcomes

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Brivaracetam as viable monotherapy option for focal and generalized epilepsy.

Epilepsy & behavior : E&B·2026

Same author

When seizure counts are not seizures: Measurement error and its implications for epilepsy management and driving policy.

Epilepsia·2026

Same author

Direct cortical stimulation-evoked symptoms in the human temporal pole: a cohort study.

Clinical neurophysiology practice·2026

Same author

Comparison of volume- and surface-based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia.

Epilepsia·2026

Same author

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders.

Epileptic disorders : international epilepsy journal with videotape·2026

Same author

Retrospective observational study of treatment and referral pathways of patients with epilepsy in Germany.

Seizure·2026

Search research articles

Related Experiment Video

Updated: Feb 6, 2026

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Removing high-frequency oscillations: A prospective multicenter study on seizure outcome.

Julia Jacobs¹, Joyce Y Wu², Piero Perucca²

¹From the Department of Neuropediatrics and Muscular Diseases (J.J., M.M.) and Epilepsy Center (J.J., A.S.-B.), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany; Division of Pediatric Neurology (J.Y.W., G.W.M.), David Geffen School of Medicine and Mattel Children's Hospital UCLA, Los Angeles, CA; and Montreal Neurological Institute (P.P., R.Z., F.D., J.G.), McGill University, Quebec, Canada. julia.jacobs@gmx.de.

|August 19, 2018

Summary

Predicting epilepsy surgery outcomes using high-frequency oscillations (HFOs) showed group-level correlation but failed individual prognostication. Further research is needed to refine HFO analysis for personalized seizure outcome prediction.

More Related Videos

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Published on: April 15, 2009

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Published on: March 10, 2017

Related Experiment Videos

Last Updated: Feb 6, 2026

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

Published on: December 6, 2016

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila

Published on: April 15, 2009

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Automatic Detection of Highly Organized Theta Oscillations in the Murine EEG

Published on: March 10, 2017

Area of Science:

Neuroscience
Epileptology
Clinical Neurology

Background:

Interictal high-frequency oscillations (HFOs) are potential biomarkers for epileptic tissue.
Predicting postsurgical seizure outcomes is crucial for epilepsy surgery planning.

Purpose of the Study:

To evaluate the predictive value of interictal HFOs for postsurgical seizure outcomes in a prospective multicenter epilepsy surgery trial.
To determine if HFO-generating tissue resection correlates with seizure freedom.

Main Methods:

Fifty-two epilepsy patients from three centers were prospectively studied over one year.
HFOs (80-250 Hz ripples, 250-500 Hz fast ripples) were detected using intracranial EEG and electrocorticography.
Surgical planning and resection extent relative to HFO-generating regions were analyzed.

Main Results:

A group-level correlation was observed between resecting HFO-generating regions and seizure-free outcomes.
Individual seizure outcome prediction was inaccurate in 33% of patients (67% true prognostication).
Some patients achieved seizure freedom without resection of the majority of HFO-generating tissue.

Conclusions:

Individual prediction of epilepsy surgery outcomes based on HFOs was not consistently possible.
Current HFO analysis techniques may require refinement or HFOs may be less specific to epileptic tissue than previously thought.