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Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
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Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
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Structural Joints: Cartilaginous Joints01:17

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Joints01:26

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Two subtypes of symptomatic joint hypermobility: a descriptive study using latent class analysis.

Francesco Di Mattia1, Robyn Fary1, Kevin J Murray2

  • 1School of Physiotherapy and Exercise Science, Curtin University, Perth, Western Australia, Australia.

Archives of Disease in Childhood
|August 19, 2018
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Summary
This summary is machine-generated.

This study identified two distinct subgroups of children with symptomatic joint hypermobility: athletic-persistent and systemic-profound. These findings aid in understanding and managing hypermobility in pediatric rheumatology.

Keywords:
developmental coordination disorderhypermobilityhypermobility spectrum disorderjoint hypermobility syndromemusculoskeletal pain

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Area of Science:

  • Pediatric Rheumatology
  • Clinical Genetics
  • Musculoskeletal Disorders

Background:

  • Symptomatic joint hypermobility in children presents a diagnostic challenge.
  • Understanding distinct clinical phenotypes is crucial for effective management.
  • Previous research has not clearly delineated subgroups within this pediatric cohort.

Purpose of the Study:

  • To investigate and identify distinct subgroups within a cohort of children experiencing symptomatic joint hypermobility.
  • To analyze clinical presentations, medical history, psychosocial factors, and physical examination findings.
  • To inform clinical decision-making and management strategies for pediatric hypermobility.

Main Methods:

  • Retrospective review of case notes for 318 children with joint hypermobility.
  • Latent class analysis utilizing seven key extracted variables.
  • Identification of subgroups based on clinical presentation, medical history, and examination findings.

Main Results:

  • Two distinct subgroups were identified: 'athletic-persistent' (62%) and 'systemic-profound' (38%).
  • The 'athletic-persistent' group exhibited recurrent musculoskeletal pain and less severe hypermobility.
  • The 'systemic-profound' group presented with generalized hypermobility, pain, gastro-oesophageal reflux, and motor delay.

Conclusions:

  • The study confirms two distinct clinical presentations in children with symptomatic joint hypermobility.
  • These findings have significant implications for tailored clinical management and treatment approaches.
  • Further research into these subgroups may optimize patient outcomes in pediatric rheumatology.