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Ultrasound Evaluation of Puncture Sites After Deployment of Two Different Types of Vascular Closure Devices: A

Young Jin Heo¹, Hae Woong Jeong², Jin Wook Baek¹

¹Department of Radiology, Inje University Busan Paik Hospital, Bokji-ro 75, Busanjin-Gu, Busan, Korea, 47392.

Cardiovascular and Interventional Radiology

|August 19, 2018

Abstract

Purpose:

The aim of this study was to compare the ultrasonographic findings of femoral puncture sites and the complications of Perclose ProGlide^® and FemoSeal™ after neurointerventional procedures.

Methods:

In this prospective, single-center study, we randomly assigned 155 femoral puncture sites to treatment with Perclose ProGlide^® or FemoSeal™. We hypothesized that the two different types of VCD cause different vascular changes. Ultrasonography of the femoral puncture sites was performed 24 h after the procedure and at an outpatient visit after 6 months. The intima-media thickness (IMT), vessel diameter, and minimal luminal diameter of the common femoral artery were measured; the perivascular soft tissue change and absorption of the hemostatic material were observed. The device failure rate and vascular complications associated with each device were also evaluated.

Results:

Follow-up ultrasonography was performed at a median follow-up time of 187.0 days (range 147-240 days) after the initial ultrasonography. The IMT on follow-up ultrasonography was significantly higher in patients who received FemoSeal™ (P = 0.0000). Intimal hyperplasia and partial absorption of the hemostatic material were significantly more frequent in patients who received FemoSeal™. The vessel diameters on initial and follow-up ultrasonography were not significantly different, but the minimal diameter on follow-up ultrasonography was significantly lower in patients who received FemoSeal™. Device failure and pseudoaneurysms occurred at 9 and 3 puncture sites in patients who received Perclose ProGlide^®, respectively.

Conclusions:

Intimal hyperplasia was more frequently observed in patients who received FemoSeal™. However, more device failures and pseudoaneurysms occurred in patients who received Perclose ProGlide^®.

Level Of Evidence:

Step 2 (level 2).

Keywords:

FemoSeal Intimal hyperplasia Intima–media thickness Perclose ProGlide Ultrasonography Vascular closure device

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