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Updated: Feb 6, 2026

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
Prefrontal activation during Stroop and Wisconsin card sort tasks in children with developmental coordination
Jennifer K Lange Koch1, Helga Miguel2, Ann L Smiley-Oyen3
1Department of Kinesiology, Iowa State University, 534 Wallace Road, Ames, IA, 50011, USA. jkparker@iastate.edu.
Abstract:
We used near-infrared spectroscopy to examine dorsolateral prefrontal cortex (DLPFC) activation over time in 10 children with or at-risk-for developmental coordination disorder (DCD) and 11 typically developing children (ages 8-12) during tasks involving executive processing. The groups performed with similar accuracy on the Stroop and Wisconsin card sort (WCST), but their underlying neural activation differed. Typically developing children modulated DLPFC activity over time and showed rightward lateralization during Stroop but no lateralization during WCST. The DCD group exhibited high and sustained activation across hemispheres and tasks, which we suggest is a compensatory effort to maintain response accuracy.
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