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Related Experiment Video

Updated: Feb 6, 2026

Transient Transduction of the Strobilated Forms of Echinococcus granulosus
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A report on three patients with Echinococcus multilocularis: Lessons learned.

Nalini Bansal1, Vivek Vij2, Mukul Rastogi3

  • 1SRL Ltd, Fortis Escorts Heart Institute, Okhla Road, New Delhi, 110 025, India. drnalinibansal@yahoo.com.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|August 20, 2018
PubMed
Summary
This summary is machine-generated.

Echinococcus multilocularis (EM) can cause lethal liver disease, mimicking cancer. This parasite invades vessels and nerves, sometimes leading to Budd-Chiari syndrome (BCS) through direct infiltration.

Keywords:
Alveolar echinococcosisBudd-Chiari syndromeEchinococcus multilocularisMalignant parasiteNeural invasion

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Area of Science:

  • Parasitology
  • Hepatology
  • Infectious Diseases

Background:

  • Echinococcus multilocularis (EM) is a highly virulent parasite causing a lethal helminthic disease in humans.
  • The disease can present as a hepatic mass, often mistaken for malignant neoplasms.
  • Vascular and neural invasion by EM can lead to diverse clinical manifestations.

Observation:

  • Three cases of EM infection are presented.
  • Case 1: Multiple hepatic space-occupying lesions.
  • Case 2: Liver mass infiltrating nerve bundles.
  • Case 3: Hepatic mass invading large vessels (inferior vena cava, right hepatic vein), presenting as Budd-Chiari syndrome (BCS).

Findings:

  • EM exhibits a significant mass-forming effect.
  • The parasite demonstrates capabilities for neural and vascular invasion.
  • Budd-Chiari syndrome (BCS) can result from direct parasitic invasion, which is rare compared to secondary compression.

Implications:

  • Highlights the diagnostic challenge of EM, particularly when mimicking malignancy.
  • Emphasizes the potential for EM to directly cause vascular complications like BCS.
  • Underscores the importance of considering parasitic infections in the differential diagnosis of complex liver pathologies.