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Updated: Feb 6, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Surgical Management of Acute and Chronic Pulmonary Embolism
Barbara L LeVarge1, Cameron D Wright2, Josanna M Rodriguez-Lopez3
1Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina, 130 Mason Farm Road CB 7020, Chapel Hill, NC 27599, USA.
Abstract:
Surgical pulmonary embolectomy and pulmonary thromboendarterectomy are well-established treatment strategies for patients with acute and chronic pulmonary embolism, respectively. For both procedures, techniques and outcomes have evolved considerably over the past decades. Patients with massive and submassive acute pulmonary embolism are at risk for rapid decline owing to right ventricular failure and shock. When thrombus is proximal, embolectomy can rapidly restore cardiac function. Chronic thromboembolic pulmonary hypertension is a more complex disease that requires skilled, careful dissection of the arterial wall, including vascular intima. When successful, surgery leads to clinical cure of the associated pulmonary hypertension, with excellent long-term outcomes.
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