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Updated: Feb 6, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
[Upper-extremity venous thrombosis: A retrospective study about 160 cases].
L Drouin1, M-A Pistorius1, A Lafforgue1
1Service de médecine interne, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes, France.
Upper limb venous thrombosis (ULVT) is frequently linked to endovenous devices. While symptomatic pulmonary embolism (PE) is uncommon, underlying conditions like malignancy and sepsis are prevalent in ULVT patients.
Area of Science:
- Vascular Medicine
- Thrombosis Research
- Diagnostic Imaging
Background:
- Upper limb venous thrombosis (ULVT) is a condition requiring thorough clinical evaluation.
- Understanding the clinical features and underlying causes of ULVT is crucial for patient management.
- Doppler ultrasonography is the primary diagnostic tool for suspected ULVT.
Purpose of the Study:
- To delineate the clinical characteristics of upper limb venous thrombosis (ULVT).
- To identify the primary etiologies and associated conditions in patients diagnosed with ULVT.
- To evaluate the diagnostic accuracy of clinical symptoms for ULVT.
Main Methods:
- Retrospective analysis of 488 patients with suspected ULVT from January to December 2016.
- Diagnosis confirmed via Doppler ultrasonography.
- Analysis of clinical features, thrombosis location, symptomatic pulmonary embolism (PE), and associated risk factors.
Main Results:
- 160 patients were diagnosed with ULVT (80 deep venous thrombosis [DVT], 80 superficial venous thrombosis [SVT]).
- Endovenous devices were present in 92.5% of ULVT cases (87.5% DVT, 97.5% SVT).
- Malignancy (43.8% DVT, 31.3% SVT), sepsis (25%), and solid neoplasia (15%) were common comorbidities. Symptomatic PE occurred in 2.5% of cases.
Conclusions:
- Endovenous devices are strongly associated with the development of ULVT.
- The incidence of symptomatic pulmonary embolism in ULVT is notably low.
- Hematological malignancies, sepsis, and neoplasia are significant underlying conditions in patients with ULVT.
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