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Updated: Feb 6, 2026

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Published on: January 30, 2020
Quality control in dual head gamma-cameras: Comparison between methods and software used for image analysis
A N Edam1, M R Fornasier2, M De Denaro2
1Radiation Safety Institute, Sudan Atomic Energy Commission, Khartoum, Sudan.
This study compared free software for nuclear medicine quality control (QC) tests against vendor software. Free tools like NMQC showed good agreement with baseline calculations, unlike vendor software, highlighting the need for independent analysis.
Area of Science:
- Medical Imaging
- Nuclear Medicine Technology
- Quality Control
Background:
- Patient radiation dose and image quality are critical in nuclear medicine (NM).
- National Electrical Manufacturers Association (NEMA) protocols are standard for gamma-camera performance but lack standardized analysis software.
- Current gamma-camera quality control (QC) relies on various protocols and vendor-specific software, leading to potential inconsistencies.
Purpose of the Study:
- To compare the accuracy of freely downloadable software (NMQC, NM Toolkit, ImageJ-NM Toolkit) against vendor QC software for analyzing gamma-camera performance using NEMA protocols.
- To evaluate the non-uniformity evaluation of gamma-camera QC tests.
- To establish a baseline for accurate image analysis in nuclear medicine.
Main Methods:
- Analyzed ten non-uniformity QC images from a dual-head gamma-camera using NEMA protocols.
- Utilized vendor QC software and three free internet-downloadable software packages (NMQC, NM Toolkit, ImageJ-NM Toolkit).
- Used Excel calculations based on NEMA procedures as the baseline for comparison.
Main Results:
- Free software (NMQC, NM Toolkit, ImageJ-NM Toolkit) demonstrated good agreement with Excel baseline calculations for non-uniformity tests (average differences < 3%).
- Vendor QC software showed significant deviations from Excel baseline calculations (average differences ranging from 14.6% to 31.9%).
- Discrepancies in results were attributed to variations in pixel size used by different software packages.
Conclusions:
- Freely downloadable software, particularly NMQC, provides accurate gamma-camera performance analysis comparable to baseline calculations.
- Vendor QC software may introduce significant errors in image analysis due to differing pixel size interpretations.
- Independent software analysis is crucial alongside vendor software to ensure reliable quality control in nuclear medicine procedures.
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