Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins

Detergents as tools in membrane biochemistry.

The Journal of biological chemistry·2001

Fast deuterium access to the buried magnesium/manganese site in cytochrome c oxidase.

Biochemistry·2001

C-terminal truncation and histidine-tagging of cytochrome c oxidase subunit II reveals the native processing site, shows involvement of the C-terminus in cytochrome c binding, and improves the assay for proton pumping.

Biochemistry·2001

Redesign of the proton-pumping machinery of cytochrome c oxidase: proton pumping does not require Glu(I-286).

Biochemistry·2000

Where is 'outside' in cytochrome c oxidase and how and when do protons get there?

Biochimica et biophysica acta·2000

Mutations in the putative H-channel in the cytochrome c oxidase from Rhodobacter sphaeroides show that this channel is not important for proton conduction but reveal modulation of the properties of heme a.

Biochemistry·2000

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Methods in enzymology·2026

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Methods in enzymology·2026

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Methods in enzymology·2026

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Methods in enzymology·2026

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Methods in enzymology·2026

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Methods in enzymology·2026

Multimodal substrate recruitment enables CTLHMKLN1 E3 ligase to target acetylated N-, C-, and internal degrons.

Nature communications·2026

Aptamer-grafted amino-functionalized covalent organic frameworks for simultaneous exceptional selectivity and high-capacity adsorption of four aflatoxins.

Talanta·2026

Enhancing the stability and solubility of esculetin by cucurbit[n]uril (n = 6-8) encapsulation: A computational study to identify the Ideal host.

Talanta·2026

Rationally designed tunable amphiphilic glycopolymers for safe and effective vaccine adjuvanticity.

RSC advances·2026

Polysaccharides from Radix Hedysari exhibited preventive effects against DSS-induced ulcerative colitis in C57BL/6 mice.

Frontiers in immunology·2026

Second-generation lectin microarray for high throughput glycan profiling of therapeutic antibodies.

AAPS open·2026

Related Experiment Videos

Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins

Related Concept Videos

Detergents as tools in membrane biochemistry.

Fast deuterium access to the buried magnesium/manganese site in cytochrome c oxidase.

C-terminal truncation and histidine-tagging of cytochrome c oxidase subunit II reveals the native processing site, shows involvement of the C-terminus in cytochrome c binding, and improves the assay for proton pumping.

Redesign of the proton-pumping machinery of cytochrome c oxidase: proton pumping does not require Glu(I-286).

Where is 'outside' in cytochrome c oxidase and how and when do protons get there?

Mutations in the putative H-channel in the cytochrome c oxidase from Rhodobacter sphaeroides show that this channel is not important for proton conduction but reveal modulation of the properties of heme a.

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Multimodal substrate recruitment enables CTLHMKLN1 E3 ligase to target acetylated N-, C-, and internal degrons.

Aptamer-grafted amino-functionalized covalent organic frameworks for simultaneous exceptional selectivity and high-capacity adsorption of four aflatoxins.

Enhancing the stability and solubility of esculetin by cucurbit[n]uril (n = 6-8) encapsulation: A computational study to identify the Ideal host.

Rationally designed tunable amphiphilic glycopolymers for safe and effective vaccine adjuvanticity.

Polysaccharides from Radix Hedysari exhibited preventive effects against DSS-induced ulcerative colitis in C57BL/6 mice.

Second-generation lectin microarray for high throughput glycan profiling of therapeutic antibodies.

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Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins

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