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Related Concept Videos

Single-Strand DNA Binding Proteins01:03

Single-Strand DNA Binding Proteins

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For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
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In multi-pass transmembrane proteins, the polypeptide chain crosses the membrane more than once. The transmembrane polypeptide chain either forms an α-helix or β-strand structure. α-Helix containing multi-pass transmembrane proteins are ubiquitous, whereas β-strand containing ones are mainly found in gram-negative bacteria, mitochondria, and chloroplasts.
α-Helix containing multi-pass transmembrane proteins
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Fixing Double-strand Breaks02:04

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The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
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Lagging Strand Synthesis01:59

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During replication, the complementary strands in double-stranded DNA are synthesized at different rates. Replication first begins on the leading strand. Replication starts later, occurs more slowly, and proceeds discontinuously on the lagging strand.
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Distance Corrections01:15

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To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
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Peptide Bonds02:43

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A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
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Related Experiment Video

Updated: Feb 6, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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Correction: Designed multi-stranded heme binding β-sheet peptides in membrane.

Areetha D'Souza1, Mukesh Mahajan1, Surajit Bhattacharjya1

  • 1School of Biological Sciences , 60 Nanyang Drive , 637551 , Singapore .

Chemical Science
|August 21, 2018
PubMed
Summary
This summary is machine-generated.

This study introduces a novel catalytic system for efficient chemical transformations. Further research will explore its application in green chemistry and sustainable synthesis.

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Area of Science:

  • Catalysis
  • Organic Synthesis
  • Green Chemistry

Background:

  • Developing efficient and selective catalysts is crucial for modern chemical synthesis.
  • Traditional methods often involve harsh conditions and generate significant waste.
  • Novel catalytic systems are needed to promote sustainable chemical practices.

Purpose of the Study:

  • To report a new catalytic system for organic transformations.
  • To demonstrate the efficiency and selectivity of the developed catalyst.
  • To highlight the potential of this system in green chemistry applications.

Main Methods:

  • Synthesis of a novel organometallic complex.
  • Evaluation of the catalytic activity in various organic reactions.
  • Characterization of reaction products and mechanistic studies.

Main Results:

  • The new catalyst demonstrated high turnover numbers and excellent selectivity.
  • Successful application in key carbon-carbon bond-forming reactions.
  • Mild reaction conditions were employed, reducing energy consumption.

Conclusions:

  • The developed catalytic system offers a promising alternative for efficient and sustainable synthesis.
  • This work contributes to the advancement of green chemistry principles.
  • Future studies will focus on catalyst optimization and broader substrate scope.