Asthma-like symptoms: is it always a pulmonary issue?

Davide Piloni1,2, Claudio Tirelli3, Rita Di Domenica1

  • 11Department of Medical Sciences and Infective Diseases, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.

Insights

Double aortic arch, a rare congenital vascular ring, can present in adulthood with persistent cough. Suspecting this anomaly is crucial for diagnosing difficult-to-treat asthma.

Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Pediatric Surgery

Background:

  • Double aortic arch is a rare congenital vascular anomaly forming a complete ring around the trachea and esophagus.
  • Typically diagnosed in infancy, symptoms often involve respiratory and gastroesophageal issues.

Observation:

  • A 20-year-old female presented with persistent dry cough, a history of childhood recurrent bronchitis, anorexia, and allergic asthma.
  • Pulmonary function tests initially suggested an intrathoracic obstruction, which persisted despite asthma treatment.

Findings:

  • Diagnostic imaging, including chest CT, echocardiography, fiberbronchoscopy, and esophageal radiography, confirmed a double aortic arch.
  • The patient's persistent respiratory symptoms were attributed to this congenital vascular anomaly.

Implications:

  • This case highlights that double aortic arch can manifest in adulthood with atypical respiratory symptoms.
  • Congenital vascular anomalies should be considered in cases of refractory asthma or persistent cough, especially when flow/volume curves indicate obstruction.
Abstract

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