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Neurotoxicology: Five new things.

Laura M Tormoehlen1, Neeraj Kumar1

  • 1Neurology and Emergency Medicine (LMT), Indiana University, Indianapolis; Neurology (NK), Mayo Clinic, Rochester, MN.

Neurology. Clinical Practice
|August 21, 2018
PubMed
Summary
This summary is machine-generated.

Neurotoxic diseases can mimic common neurological conditions. This review covers emerging neurotoxicology areas, including metal toxicities and new street drugs, aiding diagnosis and treatment.

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Area of Science:

  • Neurotoxicology
  • Neurology
  • Toxicology

Background:

  • Neurotoxic diseases often present with symptoms similar to common neurological disorders like parkinsonism, myelopathy, neuropathy, and encephalopathy.
  • Timely diagnosis and effective treatment are crucial for managing neurotoxic conditions and achieving positive patient outcomes.

Purpose of the Study:

  • To review emerging areas in neurotoxicology with a focus on new disease processes and exposure patterns.
  • To highlight specific metal toxicities and novel neurotoxins posing public health risks.

Main Methods:

  • Literature review of recent advancements in neurotoxicology.
  • Identification and analysis of emerging neurotoxic agents and associated conditions.

Main Results:

  • Discussion of three specific metal toxicities: manganism, zinc-induced copper deficiency, and cobalt-chromium neuropathy.
  • Recognition of toxin-induced posterior reversible encephalopathy syndrome (PRES) linked to a growing list of drugs.
  • Identification of synthetic cathinones and cannabinoids as significant public health threats due to widespread use and severe toxicity.

Conclusions:

  • Accurate diagnosis of neurotoxic diseases is essential for favorable outcomes.
  • Emerging neurotoxic agents, including metals and novel synthetic drugs, require increased awareness and understanding.
  • Continued research into neurotoxicology is vital for public health protection.