Facial angiofibromas treated by rapamycin 0.05% ointment and a combined laser therapy

Francesca Negosanti1, Vera Tengattini2, Carlotta Gurioli2

  • 1Centro Dermatologico, Bologna, Italy.

Abstract

Insights

Facial angiofibromas in tuberous sclerosis can cause disfigurement. A combination of topical rapamycin and laser therapy effectively treated these growths, improving patient quality of life.

Area of Science:

  • Dermatology
  • Genetics
  • Oncology

Background:

  • Tuberous sclerosis is an autosomal dominant genodermatosis causing hamartomas in multiple organs.
  • Facial angiofibromas, common in tuberous sclerosis, can lead to significant disfigurement and psychosocial distress.
  • Current treatment guidelines for facial angiofibromas are lacking, necessitating safe and effective therapeutic options.

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