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Published on: August 9, 2015
Spread of mcr-1-Driven Colistin Resistance on Hospital Surfaces, Italy
Abstract:
Plasmid-mediated colistin resistance driven by the mcr-1 gene is of great clinical concern. Its diffusion in the hospital environment is unknown. We detected mcr-1-driven resistance in 8.3% of Enterobacteriaceae isolates from hospital surfaces in Italy, which might represent a reservoir of threatening nosocomial pathogens.
Insights
The mcr-1 gene causes colistin resistance in bacteria, a significant clinical issue. This study found mcr-1 resistance on Italian hospital surfaces, highlighting a potential source of dangerous infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Environmental Health
Background:
- Plasmid-mediated colistin resistance, particularly the mcr-1 gene, poses a significant global health threat.
- The presence and spread of mcr-1 in hospital environments remain largely uncharacterized.
- Colistin is a critical last-resort antibiotic for treating multidrug-resistant Gram-negative infections.
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