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Novel biomarkers for cardiovascular risk
Raffaele Serra1,2, Nicola Ielapi1, Andrea Barbetta1
1Interuniversity Center of Phlebolymphology (CIFL). International Research & Educational Program in Clinical & Experimental Biotechnology' at the Department of Surgical & Medical Sciences University Magna Graecia of Catanzaro, Viale Europa 88100 Catanzaro, Italy.
Insights
Novel biomarkers from omics, imaging, and clinical data can improve cardiovascular risk assessment and management. This research explores new tools to better understand and predict heart and blood vessel diseases.
Area of Science:
- Biomedical research
- Cardiovascular medicine
- Biomarker discovery
Background:
- Cardiovascular diseases (CVD) are a leading cause of global morbidity and mortality.
- Accurate assessment of cardiovascular risk is crucial for effective prevention and management.
- Existing risk prediction models can be enhanced with novel biomarkers.
Purpose of the Study:
- To review the latest advancements in novel biomarkers for cardiovascular risk.
- To explore the utility of omics, imaging, and clinical data in cardiovascular risk assessment.
- To provide insights for improving the knowledge and management of cardiovascular risk.
Main Methods:
- Comprehensive literature review of recent studies on cardiovascular biomarkers.
- Analysis of emerging biomarkers from omics technologies (genomics, proteomics, metabolomics).
- Evaluation of advanced imaging techniques and clinical data integration for risk prediction.
Main Results:
- Identification of promising novel biomarkers across omics, imaging, and clinical data domains.
- Demonstration of the potential of these biomarkers to refine cardiovascular risk stratification.
- Highlighting the synergistic potential of integrating multi-modal data for enhanced prediction.
Conclusions:
- Novel biomarkers offer significant potential to improve cardiovascular risk prediction and patient outcomes.
- Integration of omics, imaging, and clinical data is key to advancing cardiovascular risk management.
- Further research and validation are needed to translate these biomarkers into clinical practice.
Abstract:
Cardiovascular disease refers to different diseases involving the heart and/or the arteries and/or the veins. Cardiovascular disease, overall considered, is a notable source of morbidity and mortality worldwide. Therefore, several research studies are dedicated to explore, by means of biomarkers, the possiblity to calculate the cardiovascular risk both for the onset and for the complications of the related clinical manifestations such as coronary artery disease, carotid artery stenosis, peripheral artery disease, arterial aneurysm, chronic venous disease and venous thromboembolism. This review discusses the most updated information in the area of the novel biomarkers related to omics, imaging techniques and clinical data, that may help physicians in order to improve the knowledge and the management of the cardiovascular risk.
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