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Clinical practice guidance for juvenile idiopathic arthritis (JIA) 2018

Nami Okamoto1, Shumpei Yokota2, Syuji Takei3

  • 1a Department of Pediatrics, Faculty of Medicine , Osaka Medical College , Takatsuki , Japan.

Modern Rheumatology
|August 22, 2018
PubMed

Insights

This updated guidance provides recommendations for diagnosing and treating juvenile idiopathic arthritis (JIA), a common pediatric rheumatic disease. It emphasizes individualized care and incorporates recent findings on JIA pathophysiology and management.

Area of Science:

  • Pediatric Rheumatology
  • Clinical Practice Guidelines
  • Immunology

Background:

  • Juvenile idiopathic arthritis (JIA) is the most prevalent rheumatic condition in children.
  • Diagnosis of JIA relies on exclusion and differentiation due to a lack of specific indicators.
  • Previous JIA guidelines were established in 2007, necessitating an update based on recent advancements.

Purpose of the Study:

  • To update and standardize the diagnosis and treatment of JIA in Japan.
  • To provide guidance for primary care pediatricians and non-pediatric rheumatologists.
  • To incorporate new findings on JIA pathophysiology and therapeutic strategies.

Main Methods:

  • Review and synthesis of recent scientific literature on JIA.
  • Inclusion of updated management protocols for JIA complications like uveitis and macrophage activation syndrome.
  • Description of current biologic therapies for JIA.

Main Results:

  • The 2018 edition offers comprehensive guidance on JIA diagnosis and treatment.
  • It addresses the management of associated conditions and infectious risks.
  • Detailed information on biologic agents is provided.

Conclusions:

  • This guidance serves as a recommendation for JIA care, adaptable to individual patient needs.
  • It aims to improve JIA medical care and patient outcomes in Japan.
  • Continuous revision is anticipated to reflect future changes in JIA management.

Keywords:
Juvenile idiopathic arthritisalgorism of treatmentbiologicsclinical practice guidancemacrophage activation syndromeuveitis

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