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Nanosensors to Detect Protease Activity In Vivo for Noninvasive Diagnostics
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Classification of prostate cancer using a protease activity nanosensor library

Jaideep S Dudani1,2, Maria Ibrahim1,3, Jesse Kirkpatrick1,3

  • 1Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139.

Proceedings of the National Academy of Sciences of the United States of America
|August 22, 2018
PubMed
Summary

New injectable biosensors detect prostate cancer protease activity, offering a noninvasive alternative to current methods. These nanosensors show promise for improved prostate cancer diagnosis and prognosis.

Keywords:
activity-based nanosensorsdiagnostic biomarkersprognostic biomarkersprostate cancerproteolytic enzymes

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