Related Experiment Video
Updated: Feb 6, 2026

A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
Trajectory log file sensitivity: A critical analysis using DVH and EPID
Wui Ann Woon1,2, Paul B Ravindran2,3, Piyasiri Ekayanake2
1Department of Radiation Oncology, The Brunei Cancer Center, Bandar Seri Begawan BG3122, Brunei Darussalam.
Trajectory log files effectively detect multileaf collimator (MLC) positioning errors in radiation therapy. This quality assurance method correlates well with dose errors, improving treatment accuracy.
Area of Science:
- Medical Physics
- Radiation Oncology
- Quality Assurance
Background:
- Quality assurance in radiation therapy is crucial for patient safety.
- Trajectory log files offer a novel method for monitoring treatment delivery accuracy.
- Electronic portal imaging device (EPID) measurements are a standard for verification.
Purpose of the Study:
- To evaluate the sensitivity of trajectory log file analysis in detecting MLC and gantry positioning errors.
- To compare log file-based quality assurance with EPID measurements using the 3%/3mm criteria.
- To analyze the correlation between gamma passing rates and dose errors.
Main Methods:
- An in-house program modified treatment plans using log file data to recalculate dose distributions.
- Recalculated dose-volume histograms (DVHs) were compared to original DVHs.
- Differences in DVH were compared with EPID dosimetry.
Main Results:
- A strong positive linear relationship was observed between MLC positioning errors and dose errors for IMRT and VMAT plans.
- Gantry positioning errors had minimal impact on VMAT delivery.
- A significant positive correlation was found between VMAT gamma passing rates (3%/3mm) and mean DVH dose error (r=0.59, P<0.001).
Conclusions:
- Trajectory log files are sensitive to systematic MLC errors and random errors in dose delivery.
- The study successfully analyzed the correlation between gamma passing rates and DVH metrics.
- Log file analysis provides a valuable tool for quality assurance in radiation therapy.
Related Concept Videos
Orthogonal Trajectories
The Mantel-Cox Log-Rank Test
Critical Region, Critical Values and Significance Level
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...
Critical Values
Critical Thinking I
Critical Thinking II

