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Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy

Covalent Immobilization of Proteins for the Single Molecule Force Spectroscopy

Published on: August 20, 2018

ABCE Proteins: From Molecules to Development.

Carla Navarro-Quiles¹, Eduardo Mateo-Bonmatí¹, José L Micol¹

¹Instituto de Bioingeniería, Universidad Miguel Hernández, Elche, Spain.

Frontiers in Plant Science

|August 22, 2018

Summary

This summary is machine-generated.

ABCE proteins, a conserved subfamily of ATP-Binding Cassette (ABC) proteins, are essential for ribosome biogenesis and recycling. These soluble proteins play crucial roles in translation and gene expression regulation across species.

Keywords:

ABCE RLI development ribosome translation

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Published on: April 24, 2014

Area of Science:

Molecular Biology
Cell Biology
Genetics

Background:

ATP-Binding Cassette (ABC) proteins are typically membrane transporters.
The ABCE subfamily, also known as RNase L inhibitor (RLI) proteins, are evolutionarily conserved soluble proteins found in eukaryotes and archaea.

Purpose of the Study:

To review the essential functions of ABCE proteins in ribosome biogenesis and recycling.
To highlight the known and proposed developmental roles of ABCE proteins in various species.
To explore the potential role of ABCE proteins in gene expression regulation.

Main Methods:

Literature review of functional analyses, primarily from studies in *Saccharomyces cerevisiae*.
Summary of current understanding of ABCE protein functions.
Analysis of evolutionary conservation and gene encoding patterns.

Main Results:

ABCE proteins are integral components of the translational apparatus.
Functional studies in yeast demonstrate essential roles in ribosome biogenesis and recycling.
ABCE proteins are present in all eukaryotes and archaea, encoded by one or two genes.

Conclusions:

ABCE proteins have fundamental roles in protein synthesis and ribosome dynamics.
These proteins are implicated in developmental processes across different organisms.
ABCE proteins may represent a novel class of regulators linking ribosome function to gene expression.