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Wilms' tumor: analysis of thirty cases
The Southeast Asian Journal of Tropical Medicine and Public Health
|December 1, 1985
Summary
This retrospective study analyzed 30 Wilms' tumor cases, revealing cure rates of 71.4% for stage II, 50% for stage III, and 29% for stage IV. Treatment involved surgery and chemotherapy, with significant complications noted.
Area of Science:
- Pediatric Oncology
- Nephrology
- Surgical Pathology
Background:
- Wilms' tumor is a significant pediatric kidney malignancy.
- Early diagnosis and treatment are crucial for improving patient outcomes.
- Understanding treatment efficacy and complications informs clinical practice.
Purpose of the Study:
- To retrospectively analyze the treatment outcomes of Wilms' tumor cases.
- To evaluate cure rates based on disease stage.
- To identify common clinical presentations and treatment-related complications.
Main Methods:
- Retrospective analysis of 30 Wilms' tumor cases treated between 1970 and 1982.
- Review of patient demographics, clinical presentation, staging, treatment modalities, and outcomes.
- Assessment of cure rates for different stages and documentation of surgical complications.
Main Results:
- The study included 14 boys and 16 girls, with a mean age of 2 years.
- Most patients presented with advanced stages (II-IV), with only 10% in stage I.
- Cure rates varied by stage: 71.4% (Stage II), 50% (Stage III), and 29% (Stage IV).
- Serious complications included surgical shock and sudden death due to tumor emboli.
Conclusions:
- Treatment for Wilms' tumor, including surgery and chemotherapy, demonstrated variable success rates depending on the stage.
- Advanced stage at presentation significantly impacts prognosis.
- The study highlights the importance of timely diagnosis and comprehensive management to mitigate severe complications and improve survival in pediatric Wilms' tumor patients.