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Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

Bashar Emon1, Jessica Bauer2, Yasna Jain3

  • 1Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, United States.

Computational and Structural Biotechnology Journal
|August 22, 2018
PubMed

Keywords:
ADAMs, AdamalysinsANGPT2, Angiopoietin 2Activin/TGFβCAF, Cancer associated fibroblastCSF-1, Colony stimulating factor 1CTGF, Connective tissue growth factorCYR61/CCN1, Cysteine-rich angiogenic inducer 61/CCN family member 1CancerECM stiffnessECM, Extracellular matrixEGF, Epidermal growth factorEMT, Epithelial to mesenchymal transitionFGF, Fibroblast growth factorGrowth factorsHGF/SF, Hepatocyte growth factor/Scatter factorIGFs, Insulin-like growth factorsIL-13, Interleukin-13IL-33, Interleukin-33IL-6, Interleukin-6KGF, Keratinocyte growth factor, also FGF7LOX, Lysyl OxidaseMMPs, Matrix metalloproteinasesMetastasisNO, Nitric oxideSDF-1/CXCL12, Stromal cell-derived factor 1/C-X-C motif chemokine 12TACs, Tumor-associated collagen signaturesTGFβ, Transforming growth factor βTNF-α, Tumor necrosis factor-αTumor biophysicsVEGF, Vascular endothelial growth factorα-SMA, α-Smooth muscle actin

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