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Updated: Feb 6, 2026

Femoral Bone Marrow Aspiration in Live Mice
Published on: July 5, 2014
[Bone marrow edema-differential diagnosis of the femoral head necrosis]
1Klinik und Poliklinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland. patrick.stumpp@medizin.uni-leipzig.de.
Abstract:
In patients with hip pain, clinical examination is of only restricted value in the differential diagnosis. Besides a patient's age, their medical history is often helpful in finding the correct diagnosis. Additionally, imaging can give valuable hints for excluding or validating a differential diagnosis. Nowadays, magnetic resonance imaging (MRI) is often used as a primary imaging modality in Germany. These MRIs show a bone marrow edema (BME) in many different pathologies. BME occurs in transitory bone marrow edema and outside of the atraumatic femoral head necrosis, concomitant with coxarthrosis, arthritis, herniation pit, and osteoid osteoma, amongst other conditions. This article describes several frequent differential diagnoses and gives hints on how to find the correct diagnosis.
Insights
Clinical examination for hip pain has limited diagnostic value. Magnetic resonance imaging (MRI) is crucial for identifying bone marrow edema (BME) and aiding differential diagnosis in hip conditions.
Area of Science:
- Radiology
- Orthopedics
- Medical Imaging
Background:
- Clinical examination of hip pain offers restricted diagnostic value.
- Patient history and imaging are essential for accurate hip pain diagnosis.
- Magnetic resonance imaging (MRI) is a primary diagnostic tool in Germany for hip pain.
Purpose of the Study:
- To outline frequent differential diagnoses for hip pain.
- To provide guidance on utilizing imaging, particularly MRI, for diagnosis.
- To highlight the significance of bone marrow edema (BME) in various hip pathologies.
Main Methods:
- Review of common hip pathologies presenting with bone marrow edema (BME).
- Discussion of differential diagnostic approaches using clinical and imaging data.
- Emphasis on the role of MRI in identifying BME and guiding diagnosis.
Main Results:
- Bone marrow edema (BME) is a common finding on MRI across diverse hip pathologies.
- BME is associated with conditions including transitory bone marrow edema, femoral head necrosis, coxarthrosis, arthritis, herniation pit, and osteoid osteoma.
- MRI findings of BME are critical for differentiating various causes of hip pain.
Conclusions:
- Accurate diagnosis of hip pain requires integrating clinical information with advanced imaging.
- MRI is indispensable for detecting bone marrow edema (BME), aiding in the differential diagnosis of hip conditions.
- Understanding BME patterns on MRI assists in distinguishing between numerous hip pathologies.
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