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Lower Regional Pediatric In-hospital Mortality Albeit Racial/ethnic Disparities
Laurens Holmes1, Isabel Morgan2, Brianne Earnest3
1Office of Health Equity & Inclusion, Nemours/Alfred I. duPont Hospital for Children, Wilmington/Newark, DE, USA; University of Delaware, Newark, DE, USA.
Insights
Pediatric in-hospital mortality was low, with initial racial disparities that disappeared after accounting for factors like illness severity and insurance. Addressing social determinants of health is key to improving child survival rates.
Area of Science:
- Pediatric Health
- Health Disparities Research
- Social Determinants of Health
Background:
- Pediatric morbidity and mortality are influenced by social determinants of health, including health inequities.
- Understanding racial/ethnic disparities in pediatric mortality is crucial for targeted interventions.
Purpose of the Study:
- To assess the cumulative incidence of pediatric mortality.
- To identify and analyze racial/ethnic disparities in pediatric mortality.
- To determine predisposing factors contributing to these disparities.
Main Methods:
- Retrospective analysis of 16,121 pediatric patient records from Nemours/Alfred I. duPont Hospital for Children (2009-2010).
- Examination of in-hospital mortality rates and prevalence odds ratios (POR) across racial/ethnic groups.
- Statistical control for confounders including severity of illness, insurance status, and length of stay.
Main Results:
- In-hospital pediatric mortality incidence was 0.49% (80 deaths), lower than the U.S. national average (0.8%-1.1%).
- Higher mortality was observed in Black/African American and 'some other race' groups compared to White/Caucasian patients.
- After adjusting for confounders, racial differences in pediatric mortality were no longer statistically significant.
Conclusions:
- The study region demonstrated a low in-hospital pediatric mortality rate.
- While initial racial disparities in mortality were observed, they did not persist after controlling for key confounding factors.
- Findings underscore the importance of social determinants of health, quality care, insurance, and early diagnosis in mitigating pediatric morbidity and mortality.
Purpose:
Variability in pediatric morbidity and mortality tends to be influenced by several factors including though not limited to social determinants of health, namely health inequity as an exposure function of health disparities. We aimed to assess the cumulative incidence of pediatric mortality, racial/ethnic disparities, and the predisposing factors for the disparities.
Method:
The current study retrospectively examined the Nemours/Alfred I. duPont Hospital for Children medical records of 16,121 patients diagnosed with any pediatric condition during 2009 and 2010.
Results:
In-hospital pediatric mortality cumulative incidence was relatively low (80 deaths, 0.49%) when compared with similar settings in the U.S. (national average range, 0.8e1.1%) during the same period. Compared with whites/Caucasians, mortality was higher among blacks/African Americans, prevalence odds ratio (POR), 1.06, 95% CI, 0.77e1.45, and higher for some other race, POR, 1.48, 95% CI, 1.06e2.10. After controlling for potential confounders (severity of illness, insurance status, and length of stay), racial differences in pediatric mortality did not persist between whites and some other race, adjusted POR, 1.08, 99% CI, 0.75e1.57.
Conclusions:
In-hospital pediatric mortality cumulative incidence was relatively low in our region, and racial disparities exist but did not persist after controlling for confounders. These findings are suggestive of the importance of social determinants of health namely quality care, adequate medical insurance, and early detection, diagnosis in pediatric morbidity and epigenomic alterations, as well as the need to go beyond the "close medical model" to improve pediatric morbidity and survival by addressing health inequity as a function of health disparities.
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