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An atypical presentation of a severe and massive atheroembolic disease

Luis Pedro Falcão1, Sara Fernandes1, Ana Cortesão Costa1

  • 1Hospital Beatriz Ângelo, Departamento de Nefrologia, Loures, Portugal.

Jornal Brasileiro De Nefrologia
|August 22, 2018
PubMed

Insights

Atheroembolic renal disease (AERD) can develop silently in patients with atherosclerosis risk factors. This case highlights a severe, spontaneous presentation without a clear inciting event, emphasizing atypical clinical courses.

Area of Science:

  • Nephrology
  • Cardiovascular Medicine
  • Pathology

Background:

  • Atheroembolic renal disease (AERD) is a kidney complication of systemic atherosclerosis.
  • It involves cholesterol crystal emboli obstructing renal blood vessels, leading to renal impairment.

Observation:

  • This report details a patient with numerous atherosclerosis risk factors.
  • The patient experienced a severe and extensive AERD presentation.
  • Notably, there was no history of an inciting event preceding the disease onset.

Findings:

  • The patient exhibited an atypical, silent, and spontaneous development of massive atheroembolic disease.
  • This contrasts with typical presentations often linked to specific triggers.

Implications:

  • This case underscores the potential for AERD to manifest unexpectedly and without obvious triggers.
  • It highlights the importance of considering AERD in patients with risk factors, even with atypical clinical courses.
  • Further research may elucidate mechanisms behind spontaneous AERD development.

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