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Evidence Base Update of Psychosocial Treatments for Pediatric Obsessive-Compulsive Disorder: Evaluating, Improving,
Jennifer Freeman1, Kristen Benito1, Jennifer Herren1
1a Alpert Medical School of Brown University, Pediatric Anxiety Research Center , Bradley Hospital.
Insights
Cognitive-behavioral therapy (CBT) remains the top treatment for pediatric obsessive-compulsive disorder (OCD). New evidence supports family-focused CBT and technology-based CBT, alongside other combined therapies, for improved youth outcomes.
Area of Science:
- Child and Adolescent Psychiatry
- Psychology
- Behavioral Science
Background:
- Pediatric obsessive-compulsive disorder (OCD) is a persistent and disabling condition often continuing into adulthood.
- Previous reviews have assessed psychosocial treatments, with this update evaluating advancements since 2014.
Purpose of the Study:
- To review and evaluate psychosocial treatments for pediatric OCD, assessing literature improvements.
- To propose a new framework for study categorization based on research questions.
- To identify predictors and moderators of treatment efficacy.
Main Methods:
- Systematic review of psychosocial treatment studies for pediatric OCD published since the last update.
- Evaluation of studies based on methodological rigor and evidence-based criteria (Journal of Clinical Child and Adolescent Psychology criteria).
- Analysis of demographic, clinical, family, and neurocognitive factors as predictors of treatment outcomes.
Main Results:
- Cognitive-behavioral therapy (CBT) is strongly supported as a first-line treatment for youth with OCD.
- Family-focused CBT is well-established; CBT combined with D-Cycloserine, Sertraline, positive family interaction therapy, and technology-based CBT are probably efficacious.
- Demographic, clinical, and family factors consistently predict CBT outcomes, while neurocognitive predictors show mixed results.
Conclusions:
- The field has advanced significantly, reinforcing CBT's efficacy for pediatric OCD.
- Further research is needed to understand the mechanisms of treatment efficacy beyond simply identifying which treatments work.
- Refined evaluation criteria and a focus on 'how and why' treatments work are crucial for future research directions.
Abstract:
Pediatric obsessive-compulsive disorder is a chronic and impairing condition that often persists into adulthood. This review refreshes the state of support for psychosocial treatments and the predictors or moderators that relate to their efficacy and evaluates how the literature has improved since the last update in 2014. A secondary goal is to propose an additional framework for the categorization of studies based on central research questions rather than treatment format. Psychosocial treatment studies conducted since the last review are described and evaluated according to methodological rigor and evidence-based classification using the Journal of Clinical Child and Adolescent Psychology evidence-based treatment evaluation criteria. Findings again converge in support of cognitive-behavioral therapy (CBT) as an effective and appropriate first-line treatment for youth with obsessive-compulsive disorder. Family-focused CBT is now well-established. A number of other treatments including CBT+ D-Cycloserine, CBT+ Sertraline, CBT+ positive family interaction therapy, and technology-based CBT are now probably efficacious. Demographic, clinical, and family factors are consistent predictors of CBT outcome with conflicting findings for neurocognitive predictors. The field has advanced significantly since the last review, but there is still room for improvement. Some of the conclusions that can be drawn may be limited by our evaluation criteria. Future directions are proposed to advance treatment outcome research beyond a focus on which treatments work to exploring factors that account for how and why they work.
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