Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioavailability: Influencing Factors01:22

Bioavailability: Influencing Factors

400
Bioavailability refers to the extent and rate at which a drug reaches systemic circulation in its active form. Extent refers to the amount of the drug that makes it into circulation, while rate is the speed at which it enters circulation. It is influenced by several factors critical for optimizing drug formulations, dosing regimens, and therapeutic outcomes.Physicochemical properties of drugs and formulationsThe solubility, stability, and dissolution rate of a drug significantly impact its...
400
Factors Influencing Microbial Growth: pH01:29

Factors Influencing Microbial Growth: pH

1.2K
Microorganisms are classified as acidophiles, neutrophiles, or alkaliphiles based on their pH growth preferences, reflecting their adaptations to specific environments. Maintaining a stable intracellular pH is critical for macromolecular stability and enzymatic activity, which can be challenged by external pH variations.Neutrophiles, such as Escherichia coli, grow optimally between pH 5.5 and 8.0. These microorganisms inhabit neutral or slightly acidic environments and employ mechanisms like...
1.2K
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

6.8K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
6.8K
Factors Influencing Attraction I: Proximity01:22

Factors Influencing Attraction I: Proximity

279
Proximity plays a fundamental role in shaping interpersonal attraction by increasing opportunities for interaction and fostering familiarity. Research consistently demonstrates that individuals are more likely to form social bonds with those who are physically closer to them, whether in residential settings, workplaces, or educational institutions. This effect is largely driven by the increased frequency of encounters, which facilitates the development of friendships and romantic...
279
Factors Influencing Attraction VI: Personality Traits01:23

Factors Influencing Attraction VI: Personality Traits

242
Personality traits are fundamental in shaping social perception and influencing interpersonal relationships. Certain traits, such as agreeableness and extraversion, contribute positively to social interactions, whereas others, such as narcissism, have complex and often contradictory effects on how individuals are perceived over time.The Role of Agreeableness and ExtraversionAgreeableness and extraversion are associated with higher levels of interpersonal attractiveness and likability.
242
Factors Influencing Bioavailability: First-Pass Elimination01:23

Factors Influencing Bioavailability: First-Pass Elimination

8.2K
When a drug is taken orally, it undergoes a journey starting from the gastrointestinal (GI) tract, passing through the portal vein, reaching the liver, and finally entering the systemic circulation. This process involves the absorption of the drug across the GI tract. The liver is the primary site for metabolizing the drug, with some metabolism also occurring in the gut wall. This journey significantly reduces the quantity of the drug that reaches the systemic circulation, a phenomenon known as...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

N,N-dimethylglycine sodium salt prevents human dermal papilla senescence and promotes hair growth in patients with pattern hair loss.

Journal of dermatological science·2026
Same author

Entrepreneurial calling and psychological wellbeing: a qualitative study of a dynamic and regulated work experience.

Frontiers in psychology·2026
Same author

The rise and fall of TRPV1-targeted analgesia in osteoarthritis: a critical appraisal.

Expert opinion on pharmacotherapy·2026
Same author

Correction: Singlár et al. Revealing the Specific Contributions of Mitochondrial CB<sub>1</sub> Receptors to the Overall Function of Skeletal Muscle in Mice. <i>Cells</i> 2025, <i>14</i>, 1517.

Cells·2026
Same author

Synthesis of condensed chiral pyranopyran derivatives with antiproliferative activity using domino Knoevenagel-IMHDA sequences.

RSC advances·2026
Same author

B-type natriuretic peptide attenuates TLR-induced cytokine and chemokine secretion in monocyte-derived Langerhans cells.

Frontiers in immunology·2026

Related Experiment Video

Updated: Feb 6, 2026

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
03:05

Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

Published on: November 21, 2025

612

Endogenous Factors That Can Influence Skin pH.

Tamás Bíró, Attila Oláh, Balázs István Tóth

    Current Problems in Dermatology
    |August 22, 2018
    PubMed
    Summary

    Human skin pH regulation is complex, involving numerous endogenous factors and mechanisms. Recent research highlights pH-sensing receptors that act as crucial transducers for cellular responses in the skin.

    Area of Science:

    • Physiology
    • Dermatology
    • Biochemistry

    Background:

    • pH regulation is a complex physiological mechanism essential for homeostasis.
    • Body pH influences molecular function, signaling, and protective roles.
    • Skin possesses a unique pH environment requiring specific regulatory systems.

    Purpose of the Study:

    • To summarize endogenous factors and mechanisms regulating skin pH.
    • To highlight the role of pH-sensing receptors in the skin.

    Main Methods:

    • Review of endogenous factors influencing skin pH.
    • Discussion of molecular systems, including pH-sensing receptors.

    Main Results:

    • Skin pH is influenced by various endogenous factors and regulatory mechanisms.

    More Related Videos

    Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
    09:09

    Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

    Published on: February 24, 2021

    3.3K
    Quantification of Endogenous Auxin and Cytokinin During Internode Culture of Ipecac
    07:57

    Quantification of Endogenous Auxin and Cytokinin During Internode Culture of Ipecac

    Published on: March 15, 2018

    9.6K

    Related Experiment Videos

    Last Updated: Feb 6, 2026

    Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
    03:05

    Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study

    Published on: November 21, 2025

    612
    Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens
    09:09

    Removal and Replacement of Endogenous Ligands from Lipid-Bound Proteins and Allergens

    Published on: February 24, 2021

    3.3K
    Quantification of Endogenous Auxin and Cytokinin During Internode Culture of Ipecac
    07:57

    Quantification of Endogenous Auxin and Cytokinin During Internode Culture of Ipecac

    Published on: March 15, 2018

    9.6K
  • pH-sensing ionotropic and metabotropic receptors are identified as key transducers of cellular pH effects.

    • Conclusions:

    • Delicate regulatory machineries control skin pH.
    • pH-sensing receptors are emerging as critical mediators of cellular responses to pH in the skin.