Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Paraneoplastic endocrine syndromes].

Y Ariyoshi

    Gan to Kagaku Ryoho. Cancer & Chemotherapy
    |June 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Paraneoplastic syndromes occur when tumors secrete substances causing distant symptoms. Ectopic hormone production by nonendocrine tumors is a common cause, leading to endocrine manifestations that can be monitored by tracking hormone levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Adenovirus vector carrying REIC/DKK-3 gene: neoadjuvant intraprostatic injection for high-risk localized prostate cancer undergoing radical prostatectomy.

    Cancer gene therapy·2016
    Same author

    The induction of antigen-specific CTL by in situ Ad-REIC gene therapy.

    Gene therapy·2016
    Same author

    Disposition of TF-PEG-Liposome-BSH in tumor-bearing mice.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2009
    Same author

    Boron neutron capture therapy for recurrent oral cancer and metastasis of cervical lymph node.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2009
    Same author

    Boron neutron capture therapy for papillary cystadenocarcinoma in the upper lip: a case report.

    International journal of oral and maxillofacial surgery·2009
    Same author

    Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small-cell lung cancer: Four-Arm Cooperative Study in Japan.

    Annals of oncology : official journal of the European Society for Medical Oncology·2006
    Same journal

    [A Case of Pulmonary Epithelioid Hemangioendothelioma Associated with Multiple Cancers].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    Same journal

    [Long-Term Survival in Three Cases with Pulmonary Metastases from Colorectal Cancer Given Low-Dose S-1 Under a Regimen Combining a Carbohydrate-Restricted Ketogenic Diet, Metformin, Vitamin D, Eicosapentaenoic Acid, and Other Complementary Therapies].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    Same journal

    [Preventive Effect of Saline Eye Wash for Eye Symptoms Due to High-Dose and Intermediate-Dose Cytarabine Therapy].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    Same journal

    [Examination of Factors Affecting the Efficacy of Naldemedine Tosilate Tablets for Opioid-Induced Constipation].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    Same journal

    [Recent Advances in the Treatment of HER2-Altered Solid Tumors].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    Same journal

    [BRAF-Mutant Solid Tumor].

    Gan to kagaku ryoho. Cancer & chemotherapy·2026
    See all related articles

    Area of Science:

    • Endocrinology
    • Oncology
    • Pathology

    Background:

    • Paraneoplastic syndromes manifest as distant signs and symptoms caused by tumors.
    • These syndromes can result from circulating substances, notably hormones, secreted by neoplasms.
    • Ectopic hormone production by nonendocrine tumors is a frequent cause of paraneoplastic endocrine syndromes.

    Purpose of the Study:

    • To define paraneoplastic syndromes and their association with ectopic hormone production.
    • To highlight common paraneoplastic endocrine syndromes like Cushing's syndrome and SIADH.
    • To emphasize the diagnostic criteria and treatment principles for these syndromes.

    Main Methods:

    • Review of literature on paraneoplastic syndromes and ectopic hormone production.
    • Clinical and pathological evidence linking tumor secretion to endocrine manifestations.

    Related Experiment Videos

  • Distinguishing paraneoplastic endocrine syndromes from other endocrine disturbances.

    • Main Results:

    • Nonendocrine tumors can ectopically produce hormones, leading to endocrine disorders.
    • Common examples include ectopic ACTH production causing Cushing's syndrome and ectopic ADH causing SIADH.
    • Hypercalcemia and hypoglycemia are also observed paraneoplastic endocrine syndromes.

    Conclusions:

    • Establishing a paraneoplastic etiology requires proof of hormone production by the tumor.
    • Treatment should target the underlying tumor, as syndrome course parallels tumor progression.
    • Ectopically produced hormones serve as valuable markers for monitoring disease activity.