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Related Experiment Video

Updated: Feb 6, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
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PillCamColon2 after incomplete colonoscopy - A prospective multicenter study.

Peter Baltes1, Marc Bota2, Jörg Albert3

  • 1Clinic for Internal Medicine, Bethesda Krankenhaus Bergedorf, Hamburg 21029, Germany. baltes@bkb.info.

World Journal of Gastroenterology
|August 23, 2018
PubMed
Summary
This summary is machine-generated.

Second-generation colon capsule endoscopy (CCE) effectively visualizes missed colonic segments after incomplete optical colonoscopy (OC), detecting significant polyps and relevant extracolonic findings. Further improvements in bowel cleansing are recommended for optimal results.

Keywords:
Cleanliness levelColon capsule endoscopyComplementation rateIncomplete colonoscopyLow volume prepMoviprepPhospho-sodaPillCamColon2Polyps

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Area of Science:

  • Gastroenterology
  • Medical Devices
  • Diagnostic Imaging

Background:

  • Incomplete optical colonoscopy (OC) limits diagnostic accuracy.
  • Second-generation colon capsule endoscopy (CCE) offers a potential solution for visualizing missed colonic segments.

Purpose of the Study:

  • To evaluate the efficacy of PillCamColon2 (CCE) in visualizing colonic segments missed by incomplete OC.
  • To assess the diagnostic yield of CCE in such cases.

Main Methods:

  • Prospective multicentre study involving 81 patients with incomplete OC.
  • Patients underwent CCE using two different low-volume preparation protocols (A and B).
  • Exclusion criteria included patients with intestinal stenosis.

Main Results:

  • CCE visualized missed colonic segments in 90% (protocol A) and 97% (protocol B) of patients.
  • Significant polyps, including adenocarcinoma, were detected in 24% of cases.
  • Additional relevant extracolonic findings were identified in eight patients.

Conclusions:

  • Second-generation CCE is valuable for evaluating patients with incomplete OC.
  • CCE detects additional relevant findings, but bowel preparation quality needs enhancement.