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Updated: Feb 6, 2026

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
Published on: May 23, 2025
Optimal introduction of laparoscopic liver resection for Child-Pugh B
Hiroaki Fuji1, Satoru Seo1, Rei Toda1
1Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Insights
Laparoscopic liver resection (LLR) is minimally invasive for Child-Pugh B liver malignancy. Lesions in the left lateral segment and exophytic tumors are suitable indications for LLR in these patients.
Area of Science:
- Hepatobiliary surgery
- Minimally invasive surgical techniques
- Oncology
Background:
- Child-Pugh B liver function presents high surgical risks.
- Indications for laparoscopic liver resection (LLR) in Child-Pugh B patients remain unclear.
- This study evaluates LLR outcomes in Child-Pugh B patients.
Purpose of the Study:
- To determine optimal indications for LLR in Child-Pugh B patients.
- To compare LLR outcomes with other liver resection methods.
- To assess the safety and efficacy of LLR for liver malignancy in Child-Pugh B patients.
Main Methods:
- Retrospective cohort study of 17 Child-Pugh B patients undergoing LLR (2005-2017).
- Comparison with LLR in Child-Pugh A patients (103 cases).
- Outcomes compared to open liver resection (19 cases) and radiofrequency ablation (RFA) (20 cases) in Child-Pugh B patients.
Main Results:
- LLR in Child-Pugh B had a higher conversion rate (35.3%) than in Child-Pugh A (3.9%).
- Successful LLR in Child-Pugh B patients showed reduced postoperative ascites and shorter hospital stays versus open resection.
- LLR was associated with more left lateral segment and exophytic tumors, lower local recurrence, and longer recurrence-free survival compared to RFA.
Conclusions:
- LLR offers minimal invasiveness for Child-Pugh B liver malignancy.
- Left lateral segment lesions and exophytic tumors are favorable indications for LLR in Child-Pugh B.
- LLR is a viable option for select Child-Pugh B patients with liver malignancy.
Introduction:
Surgery for Child-Pugh B liver function is considered risky because of its high morbidity rate and the acceptable indication criteria for laparoscopic liver resection (LLR) for Child-Pugh B patients have not been identified. We conducted a retrospective cohort study to determine the optimal introduction of LLR for Child-Pugh B patients based on our single-institute experience.
Methods:
A total of 17 Child-Pugh B patients underwent LLR between 2005 and 2017. Their clinical outcomes were compared to those of LLR for Child-Pugh A patients (103 cases), conventional open liver resection for Child-Pugh B patients (19 cases), and radiofrequency ablation (RFA) for Child-Pugh B patients (20 cases) during the same period.
Results:
LLR for Child-Pugh B patients had a significantly higher conversion rate than LLR for Child-Pugh A patients (Child-Pugh A vs B: 3.9% vs 35.3%, P < 0.01). However, patients who successfully underwent laparoscopic resection (11 cases) had fewer postoperative ascites and shorter postoperative hospital stays compared to patients who underwent conventional open liver resection. In comparison to the RFA group, the LLR group more frequently had lesions in the left lateral segment (LLR vs RFA: 50.0% vs 10.0%, P = 0.02) and exophytic tumor (21.4% vs 0%, P = 0.02) than did the RFA group. Also, compared to the RFA group, the LLR group had a lower local recurrence rate (0% vs 15%, P = 0.25) and a longer recurrence-free survival (P = 0.049), but the overall survival was similar between the two groups.
Conclusions:
In the treatment of Child-Pugh B liver malignancy, the minimal invasiveness of LLR was revealed. Our results suggest that lesions in the left lateral segment and exophytic tumors are good indications for LLR for Child-Pugh B.
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