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Updated: Feb 6, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage
Feng Yan1, Zhang Yi2, Yang Hua3
1a Department of Neurosurgery, Xuanwu Hospital , Capital Medical University , Beijing , China.
Insights
This study identified key factors influencing survival and recurrent stroke after intracerebral hemorrhage (ICH) in Chinese patients. Older age, diabetes, and specific hemorrhage locations predict worse outcomes, guiding targeted patient care.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Limited data exists on intracerebral hemorrhage (ICH) prognosis within Chinese populations.
- Understanding risk factors for mortality and recurrent stroke is crucial for improving patient outcomes.
Purpose of the Study:
- To investigate predictors of one-month and five-year mortality after spontaneous ICH.
- To identify factors associated with recurrent stroke in a Chinese cohort.
Main Methods:
- Analysis of 1187 consecutive spontaneous ICH cases admitted between September 2010 and December 2016.
- Multivariate analysis to determine independent predictors of mortality and stroke recurrence.
Main Results:
- One-month and five-year mortality rates were 12.5% and 22.2%, respectively.
- Diabetes predicted short-term mortality; older age predicted long-term mortality.
- Brain stem and intraventricular hemorrhages were associated with both short- and long-term mortality. Recurrence rate was 32.5%.
Conclusions:
- Predictors for recurrent stroke included older females, hypertension, diabetes, and brain stem hemorrhage.
- Findings can inform tailored treatment strategies and enhance healthcare quality for ICH patients.
- Identifying specific risk factors improves prognosis assessment and management of intracerebral hemorrhage.
Abstract:
Objective There are limited studies exploring prognosis after intracerebral hemorrhage (ICH) in Chinese populations. Thus, we evaluated the risk factors and predictors of mortality and recurrent stroke in a large clinical cohort at a single institution. Methods We analysed consecutive cases of spontaneous ICH at admission to our hospital from September 2010 to December 2016. Independent predictors of mortality at one month and five year follow-up, as well as stroke recurrence were analysed. Results A total of 1187 cases were included (33.5% women). The one month case fatality rate was 12.5%, and the five year mortality rate was 22.2%. In the multivariate analysis, diabetes was an independent predictor of one month case fatality, and older age (≥65 years) was an independent predictor of five year mortality. Brain stem hemorrhage and intraventricular hemorrhage were independent predictors of both short- and long-term mortality. The overall recurrence rate was 32.5% among one month survivors. Conclusion Predictors of recurrent stroke were older females, hypertension, diabetes, and brain stem hemorrhage. These findings may help to determine specific treatment strategies and improve quality of health care for such patients.
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