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Published on: December 4, 2011
Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
Rakitha Higgoda1, Dilshan Perera2, Kanapathipillai Thirumavalavan2
1National Hospital of Sri Lanka, Colombo, Sri Lanka. rakithahiggs@gmail.com.
Background:
Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been reported more frequently. We report a patient who developed multifocal motor neuropathy (MMN) with conduction blocks following dengue infection during the immediate post-infectious period. MMN is a rare neurological disorder with an autoimmune etiology and to best of our knowledge this is the first reported case of MMN occurring following dengue infection as a post dengue neurological complication.
Case Presentation:
A 20 year old Sri Lankan male who was treated for serologically confirmed dengue infection presented to us with 1 month history of bilateral hand weakness which has started 5 days after the dengue infection (5 days after the discharge). On examination he had asymmetrical motor weakness of the hands and to a lesser degree in feet. There was no sensory impairment. Nerve conduction studies confirmed MMN with conduction blocks. He was started on intravenous immunoglobulin therapy for which he showed a good response.
Conclusion:
The authors report the first case of MMN complicating dengue fever in a previously healthy male from Sri Lanka. Thus it should be borne in mind that although rare, MMN can occur as a post-infectious complication of dengue fever.
Insights
Dengue infection can rarely lead to multifocal motor neuropathy (MMN), a serious neurological condition. This case highlights MMN as a potential post-infectious complication of dengue fever.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- Dengue fever is a prevalent tropical illness with diverse post-infectious complications.
- Neurological complications following dengue infection are increasingly recognized.
Observation:
- A 20-year-old male developed bilateral hand weakness five days after dengue infection.
- Clinical examination revealed asymmetrical motor weakness in the hands and feet, without sensory impairment.
Findings:
- Nerve conduction studies confirmed multifocal motor neuropathy (MMN) with conduction blocks.
- The patient responded well to intravenous immunoglobulin therapy.
Implications:
- This is the first reported case of MMN complicating dengue fever.
- Physicians should consider MMN as a rare, potential post-infectious neurological complication of dengue.
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