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Published on: January 13, 2023
Longitudinal sonographic assessment of abdominal fat distribution from 2 to 5 years of age
Christina Brei1, Daniela Much1, Stefanie Brunner1
1Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
Insights
Longitudinal ultrasound data reveal that children
Area of Science:
- Pediatric Endocrinology
- Body Composition Analysis
- Adipose Tissue Development
Background:
- Longitudinal data on children's adipose tissue (AT) development are crucial.
- Previous research reported sonographic data on abdominal fat areas up to 1 year of age.
Purpose of the Study:
- To assess the development of abdominal fat compartments in children aged 2-5 years using sonography.
- To examine the influence of sex on fat development and its correlation with anthropometric measures.
Main Methods:
- Annual sonographic measurements of subcutaneous and preperitoneal fat areas in children aged 2-5 years.
- Analysis of sex-specific differences and correlations with BMI percentiles, skinfold thickness (SFT), and waist circumference.
Main Results:
- Subcutaneous fat areas increased modestly, with significantly greater areas in females.
- Preperitoneal fat area increased significantly over time, showing greater area in females from age 3.
- Skinfold thickness (SFT) measurements were the strongest predictors for both subcutaneous and preperitoneal fat areas.
Conclusions:
- Presents novel longitudinal ultrasound data on abdominal body fat in preschool-aged children.
- Reveals differential development of fat compartments influenced by age and sex.
- Identifies SFT measurements as the optimal predictor for abdominal fat depots in this age group.
Background:
To better understand children's adipose tissue (AT) development and distribution, longitudinal data from direct assessment methods are valuable. Previously, we reported sonographic data on abdominal subcutaneous and preperitoneal fat areas ≤1 year of age.
Methods:
Sonographic measurements were annually pursued to assess the development of fat compartments in 2-5 year-old children. The effect of sex and correlations with comprehensive anthropometry (e.g., BMI percentiles, skinfold thickness (SFT) measurements, and waist circumference) are presented.
Results:
Subcutaneous fat areas increased modestly and were significantly greater in females at each time point investigated. Preperitoneal fat area increased significantly over time (all P values < 0.001) with greater area in females from 3 years onward (e.g., at 3 years estimated mean difference -4.8 mm2; 95% CI: -8.6, -0.9; P = 0.016). The strongest correlations for subcutaneous fat area were consistently observed for SFT measurements. Preperitoneal fat area showed rather weak to moderate correlations, with greater correlation coefficients for SFT measurements compared to waist circumference.
Conclusion:
For the first time, longitudinal ultrasound data on abdominal body fat covering preschool age are presented. Evaluation revealed a differential development of fat compartments, depending on children's age and sex with SFT measurements as the best predictor for both fat depots.
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