Related Experiment Video
Updated: Feb 6, 2026

High-Throughput Dissociation and Orthotopic Implantation of Breast Cancer Patient-Derived Xenografts
Published on: December 20, 2024
Guided web-based intervention for insomnia targeting breast cancer patients: Feasibility and effect
Els Dozeman1,2,3, Irma M Verdonck-de Leeuw1,2,4,5, Josée Savard6,7
1Faculty of Behavioral and Movement Sciences, Department of Clinical- developmental- and neuro Psychology, Vrije Universiteit Amsterdam, The Netherlands.
Background:
Insomnia is highly prevalent in breast cancer (BRC) patients, but non-pharmacological treatment is not widely available. The aim of this preliminary study was to investigate whether guided cognitive behavioral therapy via the Internet (I-CBT) is a feasible and effective solution for this undertreated condition in BRC patients, and to investigate who benefits most.
Methods:
An existing evidence based I-CBT sleep intervention (I-Sleep) was adapted for BRC patients. An open mixed methods design was used including qualitative interviews and pre- and post-test questionnaires measuring sleep, fatigue, daily functioning, and psychological distress.
Results:
100 of the 171 participants (59%) completed the intervention fully and participants highly valued the intervention (7.5 out of 10). Large to small pre-post effect sizes were found on insomnia severity (d = 1.33) fatigue (d = 0.24), and daytime functioning (d = 0.30). Younger patients and patients with more severe insomnia at baseline benefited most from the intervention.
Conclusion:
The I-CBT intervention I-Sleep is feasible, well-accepted, and effective for BRC patients who suffer from insomnia, especially for younger patients and those with more severe insomnia.
More Related Videos
07:13Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
Published on: March 26, 2014
07:45Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer
Published on: May 18, 2020
Related Concept Videos
Insomnia
Multiple factors contribute...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Management of Insomnia
Targeted Cancer Therapies
There are several types of targeted therapies against...
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions