Related Experiment Video
Updated: Feb 6, 2026
08:31
Bioprinting of Hydrogel Tumor Slices as a 3D Model for Mantle Cell Lymphoma
Published on: September 12, 2025
836
Updates on Circulating Tumor DNA Assessment in Lymphoma
Justin M Darrah1,2, Alex F Herrera3
1Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA.
Current Hematologic Malignancy Reports
|August 24, 2018
Summary
Circulating tumor DNA (ctDNA) shows promise in diagnosing and monitoring various lymphoma types. Further research is needed to validate its clinical use for personalized medicine.
Area of Science:
- Oncology
- Hematology
- Molecular Diagnostics
Background:
- Circulating tumor DNA (ctDNA) analysis is an emerging field in oncology.
- Its application in lymphoma diagnosis, prognosis, and treatment monitoring is rapidly developing.
Purpose of the Study:
- To review recent advancements in ctDNA applications for lymphoma.
- To summarize novel uses of ctDNA in various lymphoma subtypes.
Main Methods:
- Literature review of recent studies on ctDNA in lymphoma.
- Analysis of ctDNA applications across different lymphoma types.
Main Results:
- ctDNA assessment is feasible across diffuse large B-cell lymphoma, follicular lymphoma, Hodgkin lymphoma, and T-cell lymphoma.
- Novel applications include prognostic models, clonal evolution studies, and early treatment response assessment.
- ctDNA shows potential for predicting targeted therapy response in personalized medicine.
Conclusions:
- ctDNA holds significant promise for multiple applications in lymphoma management.
- Validation studies are required before routine clinical implementation.
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