Related Experiment Video
Updated: Feb 6, 2026

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
Published on: January 16, 2017
[Applications on therapeutic monoclonal antibody analysis by capillary electrophoresis]
1School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Abstract:
Therapeutic monoclonal antibodies play an important role in biopharmaceuticals, and gradually become one of the main directions of the development of biological medicine. The quality control of monoclonal antibodies has also become the focus of global biopharma companies and regulatory agencies. Capillary electrophoresis has become an important tool in the analysis of monoclonal antibodies with multi-modes and high resolution. In this paper, we reviewed the application of capillary gel electrophoresis, capillary isoelectric focusing and capillary zone electrophoresis on the analysis of purity, isoelectric point/charge heterogeneity and N-glycan profiling of therapeutic monoclonal antibodies.
Related Concept Videos
Capillary Electrophoresis: Applications
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Capillary Electrophoresis: Instrumentation
Therapeutic Drug Monitoring: Drug Analysis Methods
Capillary Beds
Capillaries connect arterioles, small branches of arteries, to venules,...
Capillary Exchange
Electrophoresis: Overview
There...

