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Updated: Feb 6, 2026

Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation
Published on: June 14, 2014
[Motor cortex stimulation in deafferentation facial pain]
G I Moysak1, D A Rzaev1, V M Dzhafarov2
1Federal Center of Neurosurgery, Novosibirsk, Russia; Institute of Medicine and Psychology, Novosibirsk State University, Novosibirsk, Russia.
Motor cortex stimulation offers a promising treatment for deafferentation facial pain, with significant pain reduction observed in most patients. This neurosurgical approach provides meaningful relief for debilitating facial pain conditions.
Area of Science:
- Neurosurgery
- Pain Management
- Neurology
Background:
- Deafferentation facial pain is a challenging condition often poorly controlled by conventional treatments.
- Motor cortex stimulation (MCS) is an emerging neuromodulation technique for refractory neuropathic pain.
Purpose of the Study:
- To evaluate the efficacy of motor cortex stimulation in patients with poorly controlled deafferentation facial pain.
- To review current literature on MCS for facial pain.
Main Methods:
- Eight patients with deafferentation facial pain received constant motor cortex stimulation.
- Pain severity was assessed using validated scales (VAS, BNIPS, McLaughlin) pre- and post-operatively and during follow-up.
Main Results:
- Immediate post-operative pain reduction of 80-100% in 4 patients.
- Average pain reduction of 55% at hospital discharge.
- Good to very good outcomes reported by 7 out of 8 patients during follow-up.
Conclusions:
- Motor cortex stimulation is a viable treatment option for deafferentation facial pain.
- Even modest pain reduction can be clinically significant for patients with debilitating pain.
- Further research is needed to optimize patient selection and enhance MCS efficacy.
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