Related Experiment Video
Updated: Feb 6, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
TIGR matrix for implant-based breast reconstruction - a long-term resorbable mesh
Giulio Cuffolo1, Nicholas C Holford1, Kaiyumars Contractor1
1a Frimley Health NHS Foundation Trust , Wexham Park Hospital , Slough , UK.
This study evaluated TIGR Matrix, a resorbable synthetic mesh, for breast reconstruction. Obesity was linked to higher mesh complications, but overall rates were comparable to other synthetic meshes, suggesting potential for wider use.
Area of Science:
- Plastic Surgery
- Biomaterials
- Surgical Innovation
Background:
- Biological and synthetic meshes are established for implant-based breast reconstruction.
- Single-stage direct-to-implant breast reconstruction offers advantages over traditional two-stage methods.
- Limited long-term data exists for resorbable synthetic meshes in breast reconstruction.
Purpose of the Study:
- To evaluate the outcomes of TIGR Matrix, a long-term resorbable synthetic mesh, in breast reconstruction.
- To assess mesh-related complications and identify associated risk factors.
- To contribute data on the long-term efficacy of synthetic meshes in aesthetic and reconstructive breast surgery.
Main Methods:
- Retrospective observational study of 49 patients (60 breasts) undergoing breast reconstruction with TIGR Matrix.
- Follow-up period of mean 12 months.
- Analysis of operative methods and complication rates, including correlation with patient factors like obesity.
Main Results:
- A cumulative mesh complication rate of 5.4% was reported.
- One implant explantation occurred due to infection.
- Obesity was identified as a significant risk factor for mesh-related complications.
Conclusions:
- TIGR Matrix demonstrates acceptable complication rates in breast reconstruction, comparable to other synthetic meshes.
- Obesity is a significant predictor of mesh-related complications, warranting careful patient selection.
- This study supports the potential for increased use of cost-effective resorbable synthetic meshes in breast reconstruction.
Related Concept Videos
Mesh Analysis
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
Mesh Analysis with Current Sources
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
The Extracellular Matrix
Long-term Depression
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Mesh Analysis for AC Circuits
The process of harmonizing these impedances begins with a clear understanding of the input and output signals. Once these signals are known, the...

