Human Genetics
Obsessive-Compulsive Disorder
Pleiotropy
Personality Disorders: Dependent and Obsessive-Compulsive
Attention-Deficit/Hyperactivity Disorder
Behavioral Genetics and Its Designs
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Updated: Dec 31, 2025

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
Samuel R Chamberlain1, Jon E Grant2
1Department of Psychiatry,University of Cambridge,Cambridge,UK.
The catechol-o-methyl transferase (COMT) Val158Met polymorphism is linked to higher compulsivity scores. This genetic variation influences compulsivity, a key trait in psychiatric disorders and normal behavior.
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