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Updated: Jan 5, 2026

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
Numerical simulation of the coalescence of two bubbles in an ultrasound field
1Institute of Acoustics, Tongji University, Shanghai 200092, China.
Abstract:
The coalescence of two bubbles under ultrasound irradiation is numerically investigated. The results indicate that ultrasound may accelerate the coalescence process, depending on the initial phase. The time-averaged nonzero Bjerknes force promotes bubble coalescence by dragging bubbles to nodes or antinodes, depending on their size. At the beginning of the coalescence process, a film forms between the two bubbles. The film drainage time first increases then decreases as a function of initial distance. This study contributes to an understanding of the effects of ultrasound on bubble coalescence.
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