Related Experiment Video
Updated: Feb 6, 2026
06:52
CRISPR-Cas9-Mediated Precise Knock-In Edits in Zebrafish Hearts
Published on: September 13, 2022
4.0K
Author Correction: Precision genome engineering through adenine base editing in plants
Beum-Chang Kang1,2, Jae-Young Yun1, Sang-Tae Kim1
1Center for Genome Engineering, Institute for Basic Science, Daejeon, Republic of Korea.
Nature Plants
|August 25, 2018
Summary
A correction has been made to the DNA sequence of nickase Cas9 in Supplementary Fig. 1b. This amendment ensures the accuracy of the genetic information presented in the publication.
Area of Science:
- Molecular Biology
- Genetics
Context:
- A previous version of Supplementary Fig. 1b contained an error in the DNA sequence.
- The error pertained to the sequence of nickase Cas9.
Purpose:
- To correct an error in the published DNA sequence.
- To ensure the scientific accuracy of the provided data.
Summary:
- The DNA sequence for nickase Cas9 in Supplementary Fig. 1b has been corrected.
- The amended sequence is now accurately represented.
Impact:
- Ensures reliable data for researchers using Cas9.
- Maintains the integrity of genetic research findings.
Related Concept Videos
02:23RNA Editing
9.9K
RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
9.9K
02:20Milgram's Obedience to Authority
7.4K
Obedience to authority is classically demonstrated in a more famous series of social psychology experiments performed by Stanley Milgram. He was a social psychology professor at Yale who was influenced by the trial of Adolf Eichmann, a Nazi war criminal. Eichmann’s defense for the atrocities he committed was that he was “just following orders.”
7.4K
01:28CRISPR/Cas9 Genome Editing
1.9K
The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
1.9K
00:49What is Genetic Engineering?
80.3K
Overview
80.3K
01:15Distance Corrections
293
To achieve precise distance measurements, especially in surveying and construction, certain corrections must be applied to account for potential sources of error like the standardization errors, temperature variations, and slope adjustments.Standardization error emerges when measurement equipment undergoes changes, such as wear, repairs, or weather impacts. To address this, surveyors compare the equipment’s readings to a standard. This process identifies any deviation that might lead to...
293
03:21Genome Size and the Evolution of New Genes
9.1K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.1K