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Updated: Feb 6, 2026

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
Published on: April 18, 2019
Susumu Miyake1, Makio Sugita, Tomio Okazaki
1Department of Pediatrics, Tokiwa-Kure Facilities for Persons with Severe Motor and Intellectual Disabilities, Kure, Hiroshima 737-0024, Japan.kure.miyake@tokiwa-kure.jp.
Topiramate (TPM) can induce microseizures, characterized by brief eye-opening during sleep, in patients with epilepsy and trisomy 21. These seizures resolved after discontinuing TPM, suggesting a potential side effect of this antiepileptic drug.
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