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Updated: Feb 6, 2026

How to Build a Laser Speckle Contrast Imaging LSCI System to Monitor Blood Flow
Published on: November 11, 2010
Effect of Anodal Direct-Current Stimulation on Cortical Hemodynamic Responses With Laser-Speckle Contrast Imaging
Shuo Hu1, Tao Zheng2, Yanchao Dong2
1Institute of Electrical Engineering, Yanshan University, Qinhuangdao, China.
Abstract:
Transcranial direct-current stimulation (DCS) offers a method for noninvasive neuromodulation usable in basic and clinical human neuroscience. Laser-speckle contrast imaging (LSCI), a powerful, low-cost method for obtaining images of dynamic systems, can detect regional blood-flow distributions with high spatial and temporal resolutions. Here, we used LSCI for measuring DCS-induced cerebral blood flow in real-time. Results showed that the change-rate of cerebral blood flow could reach approximately 10.1 ± 5.1% by DCS, indicating that DCS can increase cerebral blood flow and alter cortical hemodynamic responses. Thus, DCS shows potential for the clinical treatment and rehabilitation of ischemic strokes.
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