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Related Experiment Video

Updated: Feb 6, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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[Sleep endoscopy and complete concentric collapse in CPAP failure].

K Hasselbacher1, K-L Bruchhage1, N Abrams1

  • 1Klinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Universität zu Lübeck, Ratzeburger Allee, 23538, Lübeck, Deutschland.

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|August 25, 2018
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Summary
This summary is machine-generated.

Drug-induced endoscopy (DISE) helps identify obstructive sleep apnea (OSA) treatment issues. Findings show upper airway collapse patterns, body mass index, and tonsillectomy influence CPAP therapy success.

Keywords:
Drug induced sleep endoscopyHypoglossal nerve stimulationPositive airway pressureSleep surgeryUpper Airway stimulation

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Area of Science:

  • Sleep Medicine
  • Otolaryngology
  • Respiratory Medicine

Background:

  • Continuous positive airway pressure (CPAP) is the primary treatment for obstructive sleep apnea (OSA).
  • Many OSA patients struggle with sufficient CPAP adherence.
  • Drug-induced endoscopy (DISE) allows assessment of upper airway collapse patterns.

Purpose of the Study:

  • To evaluate patients with CPAP usage problems using DISE.
  • To identify specific causes of CPAP non-adherence.
  • To provide tailored therapy recommendations based on DISE findings.

Main Methods:

  • Retrospective analysis of 210 OSA patients over 5 years.
  • Inclusion criteria: apnea-hypopnea index (AHI) ≥ 15/h.
  • Evaluation using DISE to determine upper airway collapse patterns and analysis of recommended treatments.

Main Results:

  • Two-thirds of patients reported mask issues causing CPAP non-adherence.
  • Complete concentric collapse (CCC) was excluded in 75% of patients.
  • Higher BMI (>35 kg/m²) and absence of tonsillectomy (TE) correlated with increased likelihood of CCC.

Conclusions:

  • DISE is valuable for understanding CPAP non-adherence in OSA.
  • Treatment recommendations for OSA should consider CCC, BMI, and prior TE.
  • Personalized treatment strategies improve CPAP therapy outcomes.