Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

7.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.4K
Doppler Effect - I00:56

Doppler Effect - I

6.4K
The Doppler effect and Doppler shift were named after the Austrian physicist and mathematician Christian Johann Doppler in 1842, who conducted experiments with both moving sources and moving observers. Consider an observer standing on a street corner, observing an ambulance with a siren sound passing by at a constant speed. The observer experiences two characteristic changes in the sound of the siren. Initially, the sound increases in loudness as the ambulance approaches and decreases in...
6.4K
Doppler Effect - II01:05

Doppler Effect - II

4.8K
The Doppler effect has several practical, real-world applications. For instance, meteorologists use Doppler radars to interpret weather events based on the Doppler effect. Typically, a transmitter emits radio waves at a specific frequency toward the sky from a weather station. The radio waves bounce off the clouds and precipitation and travel back to the weather station. The radio frequency of the waves reflected back to the station appears to decrease if the clouds or precipitation are moving...
4.8K
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

4.8K
The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
4.8K
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

2.5K
To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
2.5K
Skin Cancer01:30

Skin Cancer

5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal health in underserved tribal India.

Sexual and reproductive health matters·2019
See all related articles

Related Experiment Video

Updated: Feb 6, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

9.9K

Monitoring tumor progression by mapping skin microcirculation with laser Doppler flowmetry.

Tanvi Pedanekar1, Rohit Kedare1, Amit Sengupta2

  • 1Bioengineering Lab, Office PS - 113, Advanced Centre for Treatment, Research and Education in Cancer, TATA Memorial Centre (TMC-ACTREC), Kharghar, Navi Mumbai, 410210, India.

Lasers in Medical Science
|August 25, 2018
PubMed
Summary

Laser Doppler flowmetry (LDF) monitors microvascular blood flow noninvasively. An innovative technique minimizes motion artifacts, enhancing analysis of blood perfusion signals from skin lesions.

Keywords:
ArtifactsColor heat mapFluxLaser Doppler blood flow meterMATLAB

More Related Videos

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat
09:28

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat

Published on: May 30, 2018

10.6K
Laser Doppler Perfusion Imaging in the Mouse Hindlimb
14:45

Laser Doppler Perfusion Imaging in the Mouse Hindlimb

Published on: April 18, 2021

6.7K

Related Experiment Videos

Last Updated: Feb 6, 2026

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry
07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

9.9K
Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat
09:28

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat

Published on: May 30, 2018

10.6K
Laser Doppler Perfusion Imaging in the Mouse Hindlimb
14:45

Laser Doppler Perfusion Imaging in the Mouse Hindlimb

Published on: April 18, 2021

6.7K

Area of Science:

  • Biomedical Engineering
  • Dermatology
  • Microcirculation Research

Background:

  • Laser Doppler flowmetry (LDF) is a noninvasive technique for assessing microvascular blood flow.
  • Monitoring blood perfusion is crucial for evaluating various physiological and pathological conditions.
  • Movement artifacts from cables, probes, or patient motion can compromise LDF signal integrity.

Purpose of the Study:

  • To develop an innovative technique to overcome limitations in LDF measurements caused by motion artifacts.
  • To improve the accuracy and reliability of microvascular blood flow monitoring.
  • To facilitate easier analysis and interpretation of LDF data for clinical applications.

Main Methods:

  • Utilized a simple analog-based laser Doppler flow meter to record biosignals.
  • Developed a novel technique to remove continuous artifacts generated by movement.
  • Processed acquired blood flux signals using MATLAB to create color heat maps for visualization.

Main Results:

  • Successfully minimized noise and artifacts caused by cable, probe, and patient movement.
  • Generated color heat maps in MATLAB for intuitive visualization of blood flow changes.
  • Enabled enhanced analysis and interpretation of microvascular perfusion over time and across areas.

Conclusions:

  • The developed technique effectively removes motion artifacts, enhancing LDF reliability.
  • Color heat map visualization aids clinicians in understanding dynamic blood flow patterns.
  • This innovation improves the utility of LDF for assessing microvascular function in skin lesions.