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[Comorbid cognitive impairments in children with nocturnal enuresis and their treatment]

L S Chutko1, S Yu Surushkina1, E A Yakovenko1

  • 1Bekhtereva Institute of Human Brain, Russian Academy of Sciences, St. Petersburg, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|August 25, 2018
PubMed

Insights

Children with enuresis exhibit cognitive deficits in memory and attention. Cerebrolysin treatment significantly improved these functions in 80% of pediatric patients, demonstrating high efficacy and safety.

Area of Science:

  • Pediatric Neurology
  • Neuropsychology

Background:

  • Children with enuresis often present with comorbid cognitive impairments.
  • Understanding these deficits is crucial for effective treatment strategies.

Purpose of the Study:

  • To investigate cognitive impairments in children with enuresis.
  • To evaluate the efficacy and safety of cerebrolysin for treating these comorbid conditions.

Main Methods:

  • Seventy children (7-10 years) with primary monosymptomatic enuresis were assessed.
  • Neuropsychological tests evaluated auditory-verbal and visual memory, inattention, and impulsivity.
  • Electroencephalography (EEG) was utilized to examine brain activity.

Main Results:

  • Enuretic children showed poorer performance in memory and attention tasks compared to controls.
  • EEG revealed activation deficits and synchronized thalamic activity.
  • Cerebrolysin treatment resulted in improvement in 80% of the patients.

Conclusions:

  • Cognitive impairments, including memory and attention deficits, are prevalent in children with enuresis.
  • Cerebrolysin demonstrates high efficacy and safety in addressing these comorbid cognitive issues.
Abstract

Keywords:
cerebrolysincognitive impairmentenuresis

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