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Updated: Feb 6, 2026
09:13
Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
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[Epilepsy and autism spectrum disorders in children]
E D Belousova1, N N Zavadenko1
1N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|August 25, 2018
Summary
Epilepsy and autism spectrum disorders (ASD) frequently co-occur in children. This review examines their association, genetic links, and treatment considerations for ASD patients.
Area of Science:
- Neuroscience
- Pediatrics
- Genetics
Background:
- Epilepsy and autism spectrum disorders (ASD) are frequently comorbid in children.
- Understanding the relationship between these conditions is crucial for effective management.
Purpose of the Study:
- To review the incidence and types of epilepsy and ASD co-occurrence.
- To explore the genetic underpinnings of this comorbidity.
- To discuss practical management strategies, including antiepileptic drug use in children with ASD.
Main Methods:
- Review of incidence data for ASD in epilepsy and vice versa.
- Analysis of epileptiform discharges on EEG in ASD.
- Examination of different models for epilepsy and ASD co-occurrence.
Main Results:
- Multiple patterns of epilepsy and ASD co-occurrence exist, ranging from independent conditions to shared genetic causes or causal relationships.
- Specific genetic factors contribute to the comorbidity of epilepsy and ASD.
- The epileptic process itself may influence brain networks critical for social and communication development in ASD.
Conclusions:
- The comorbidity of epilepsy and ASD is complex, with various potential underlying mechanisms.
- Genetic factors play a significant role in the co-occurrence of these conditions.
- Rational use of antiepileptic drugs is essential for children with ASD and epilepsy.
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