Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Auditory time perception in Huntington's disease.

S Vez1, J Köhli1, B Frey1

  • 1Swiss Huntington's Disease Centre, Neurozentrum Siloah, Gümligen, Switzerland.

Neuropsychologia
|August 25, 2018
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Is less more? Revisiting elective nodal irradiation in head and neck cancer.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·2025
Same author

Warming and rainfall reduction alter soil microbial diversity and co-occurrence networks and enhance pathogenic fungi in dryland soils.

The Science of the total environment·2024
Same author

Neutrophils seeking new neighbors: radiotherapy affects the cellular framework and the spatial organization in a murine breast cancer model.

Cancer immunology, immunotherapy : CII·2024
Same author

European consensus statement on expert colposcopy.

European journal of obstetrics, gynecology, and reproductive biology·2023
Same author

Current exposure to a second language modulates bilingual visual word recognition: An EEG study.

Neuropsychologia·2021
Same author

Algorithmic assessment of cellular senescence in experimental and clinical specimens.

Nature protocols·2021
Same journal

Prevalence and modulation of rat off-track head scanning on linear tracks: possible implications for representational and dynamic properties of hippocampal place cells.

Neuropsychologia·2026
Same journal

Identifying networks within an fMRI multivariate searchlight analysis.

Neuropsychologia·2026
Same journal

Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

Neuropsychologia·2026
Same journal

Deficient processing of regularity violations during visuospatial neglect: a visual mismatch negativity study.

Neuropsychologia·2026
Same journal

Seeing is believing: mental imagery amplifies moral, emotional, and motivational responding to mentally constructed hypothetical events.

Neuropsychologia·2026
Same journal

From past recall to future projection: What does verb tense production reveal about mental time travel in Alzheimer's disease?

Neuropsychologia·2026
See all related articles

Huntington's disease (HD) gene carriers show impaired time perception, especially those with motor symptoms. This auditory timing deficit worsens with disease progression and may involve cognitive processes similar to those in the Stroop test.

Area of Science:

  • Neuroscience
  • Genetics
  • Auditory Perception

Background:

  • Huntington's disease (HD) primarily affects the striatum, impacting motor control and timing.
  • Auditory time perception in pre-motor or early-motor stage HD gene carriers is not well understood.

Purpose of the Study:

  • To evaluate time perception performance in HD gene carriers with varying motor involvement.
  • To explore potential therapeutic targets and disease progression markers for HD.

Main Methods:

  • Assessed absolute (duration-based) and relative (beat-based) time perception in HD mutation carriers (pre-motor and motor stages) and healthy controls.
  • Measured thresholds of time difference perception and correlated them with clinical scores and cognitive tests.

Main Results:

Keywords:
Huntington's diseasePerceptionTime

Related Experiment Videos

  • HD-motor patients exhibited poorer performance in both time perception tasks compared to HD-premotor carriers and controls.
  • Time perception thresholds correlated with disease progression scores (CAP) and cognitive tests (Stroop, Trail Making B).

Conclusions:

  • Auditory time perception deficits in HD correlate with disease advancement.
  • Time perception in HD may rely on cognitive mechanisms shared with executive functions like those assessed by the Stroop test.