Related Experiment Video
Updated: Feb 6, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
Whole spine localizers of magnetic resonance imaging detect unexpected vertebral fractures
Malwina Kaniewska1, Johannes Maria de Beus2, Frank Ahlhelm1
11 Institute of Radiology, Kantonsspital Baden, Baden, Switzerland.
Background:
Whole spine localizers (WS-loc) of magnetic resonance imaging (MRI) are performed for enumeration of the vertebrae but they can be also used for the evaluation of the spine.
Purpose:
To assess the accuracy of fracture detection using WS-locs of MRI and compare the findings with standard high-resolution short tau inversion recovery (STIR) sequences, and to determine whether the review of WS-locs is useful and if additional information can be gained by assessing the thoracic spine section of the WS-locs.
Material And Methods:
A total of 298 magnetic resonance (MR) examinations of the lumbar spine with WS-locs were evaluated. Two independent readers reviewed the images. In case of fracture detection, further characterization of the fracture was performed. To assess inter-reader agreement, unweighted Cohen's kappa with 95% confidence intervals (CI) and Phi coefficients were calculated.
Results:
The study sample included 187 female and 111 male patients (age range = 65-94 years; median age = 75.0 years). The WS-locs detected 42 fractures of the lumbar spine and 36 of the thoracic spine. Inter-reader agreement for fracture detection in the lumbar and thoracic spine was strong (K = 0.87, 95% CI = 0.78-0.95, Phi = 0.87, and K = 0.88, 95% CI = 0.79-0.96, Phi = 0.88, respectively).
Conclusion:
WS-locs from MR examinations of the lumbar spine provide a good diagnostic tool for the detection and evaluation of unsuspected vertebral fractures. WS-locs show strong inter-reader agreement for fracture detection in the thoracic and lumbar spine.
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies IV: Magnetic Resonance Imaging
Atomic Nuclei: Magnetic Resonance
Resonance
Nuclear Magnetic Resonance (NMR): Overview
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
Muscles of the Vertebral Column
Superficial Layer:
The superficial layer consists primarily of the splenius muscles, which include the splenius capitis and splenius cervicis. These muscles are mainly responsible for the head and cervical spine movements, including extension, rotation, and lateral bending. The splenius capitis...

